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The Longevity of Sirtuins

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2012 English Publisher:Elsevier BVJournal:Cell Reports, volume 2, pages 1,473-1,474 (issn: 2211-1247, Copyright policy )
Authors: David Sinclair; Eric Verdin;

doi: 10.1016/j.celrep.2012.12.004

pmid: 23273894

The Longevity of Sirtuins

Abstract

Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.

Related Organizations
Keywords

QH301-705.5, Fat Body, Longevity, Animals, Drosophila Proteins, Sirtuins, Biology (General), Histone Deacetylases, Diet

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 13
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Average
Top 10%
Top 10%
gold