
pmid: 28283067
The subfamily C ATP-binding cassette (ABCC) transporters mediate multidrug resistance and ion conductance regulation. Recent atomic or near-atomic resolution structures of three physiologically significant ABCC transporters (MRP1, SUR1, and CFTR), determined by using single-particle cryo-electron microscopy (cryo-EM), reveal structural details that help explain the wide functional diversity of this ABC transporter subfamily.
ATP-Binding Cassette, Sub-Family C Proteins, Membrane Transport Proteins, ATP-Binding Cassette Transporters
ATP-Binding Cassette, Sub-Family C Proteins, Membrane Transport Proteins, ATP-Binding Cassette Transporters
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