descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2015 English Publisher:Elsevier BVJournal:Cell, volume 162, pages 474-475 (issn: 0092-8674,

Authors: Linnaea E. Ostroff; Hongkui Zeng;

doi: 10.1016/j.cell.2015.07.031

pmid: 26232218

Electron Microscopy at Scale

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Abstract

The essential details of cellular interactions at synaptic level in the brain are still largely unknown. In this issue, Kasthuri et al. report new experimental and computational technologies for large-scale electron microscopy data collection and analysis, and through saturated reconstruction uncover synaptic connectional specificity that cannot be predicted by simple axonal-dendritic proximity.

Related Organizations

Allen Institute
United States
Allen Institute
United States
Allen Institute for Brain Science
United States

Keywords

Neurons, Biochemistry, Genetics and Molecular Biology(all), Microscopy, Electron, Scanning, Animals, Neocortex, Microtomy

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Saturated Reconstruction of a Volume of Neocortex
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