Macrolides: The Plug Is Out

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2012 Germany English Publisher:Elsevier BVJournal:Cell, volume 151, pages 469-471 (issn: 0092-8674,

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Authors: Gamerdinger, Martin; Deuerling, Elke;

doi: 10.1016/j.cell.2012.10.015

pmid: 23101618

Macrolides: The Plug Is Out

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Abstract

Macrolide antibiotics are thought to clog up the ribosomal tunnel and thereby block general protein synthesis. By using a combination of elegant in vivo and in vitro approaches, Kannan et al. show that the inhibitory action of these drugs on bacterial protein synthesis is selective rather than global.

Country

Germany

Related Organizations

University of Konstanz
Germany

Keywords

info:eu-repo/classification/ddc/570, Biochemistry, Genetics and Molecular Biology(all)

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