
pmid: 22726432
We provide here a molecular movie that captures key aspects of RNA polymerase II initiation and elongation. To create the movie, we combined structural snapshots of the initiation-elongation transition and of elongation, including nucleotide addition, translocation, pausing, proofreading, backtracking, arrest, reactivation, and inhibition. The movie reveals open questions about the mechanism of transcription and provides a useful teaching tool.
Bacteria, Transcription, Genetic, Biochemistry, Genetics and Molecular Biology(all), Motion Pictures, Fungi, Humans, RNA Polymerase II, Archaea, Transcription Factors
Bacteria, Transcription, Genetic, Biochemistry, Genetics and Molecular Biology(all), Motion Pictures, Fungi, Humans, RNA Polymerase II, Archaea, Transcription Factors
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
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