Hypoxia-Inducible Factors in Physiology and Medicine
Copyright policy )Hypoxia-Inducible Factors in Physiology and Medicine
Oxygen homeostasis represents an organizing principle for understanding metazoan evolution, development, physiology, and pathobiology. The hypoxia-inducible factors (HIFs) are transcriptional activators that function as master regulators of oxygen homeostasis in all metazoan species. Rapid progress is being made in elucidating homeostatic roles of HIFs in many physiological systems, determining pathological consequences of HIF dysregulation in chronic diseases, and investigating potential targeting of HIFs for therapeutic purposes.
- Johns Hopkins Medicine United States
- Johns Hopkins University School of Medicine United States
- JOHNS HOPKINS UNIVERSITY
Basic Helix-Loop-Helix Proteins, Oxygen, Biochemistry, Genetics and Molecular Biology(all), Chronic Disease, Animals, Embryonic Development, Humans, Hypoxia, Biological Evolution
Basic Helix-Loop-Helix Proteins, Oxygen, Biochemistry, Genetics and Molecular Biology(all), Chronic Disease, Animals, Embryonic Development, Humans, Hypoxia, Biological Evolution
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