Feedback on Fat: p62-mTORC1-Autophagy Connections
Copyright policy )Feedback on Fat: p62-mTORC1-Autophagy Connections
Metabolic homeostasis requires integration of multiple signals and cellular activities. Without this integration, conditions of obesity and diabetes often develop. Recent in vivo studies explore the molecular basis for metabolic homestasis, showing that p62 links autophagy and mTORC1 activation to regulate adipogenesis and energy control.
- Sanford Burnham Prebys Medical Discovery Institute United States
Inflammation, Adipogenesis, Biochemistry, Genetics and Molecular Biology(all), Mice, Metabolic Diseases, Multiprotein Complexes, Autophagy, Animals, Homeostasis, Humans, Adaptor Proteins, Signal Transducing, Transcription Factors
Inflammation, Adipogenesis, Biochemistry, Genetics and Molecular Biology(all), Mice, Metabolic Diseases, Multiprotein Complexes, Autophagy, Animals, Homeostasis, Humans, Adaptor Proteins, Signal Transducing, Transcription Factors
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