Asthma and Allergic Inflammation

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2010 English Publisher:Elsevier BVJournal:Cell, volume 140, pages 777-783 (issn: 0092-8674,

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Authors: Locksley, Richard M.;

doi: 10.1016/j.cell.2010.03.004

pmid: 20303868

pmc: PMC3134388

Asthma and Allergic Inflammation

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Abstract

Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.

Related Organizations

Howard Hughes Medical Institute
United States
University of California, San Francisco
United States

Keywords

Biochemistry, Genetics and Molecular Biology(all), Respiratory Hypersensitivity, Animals, Humans, Respiratory Mucosa, Asthma, Immunity, Innate

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