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Cell
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TRIM-NHL Proteins Take on miRNA Regulation

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Mar 2009 English Publisher:Elsevier BVJournal:Cell, volume 136, pages 818-820 (issn: 0092-8674, Copyright policy )
Authors: Loedige, Inga; Filipowicz, Witold;

doi: 10.1016/j.cell.2009.02.030

pmid: 19269362

TRIM-NHL Proteins Take on miRNA Regulation

Abstract

The TRIM-NHL family of proteins is conserved among metazoans and has been shown to regulate cell proliferation and development. In this issue, Hammell et al. (2009) and Schwamborn et al. (2009) identify two members of this protein family, NHL-2 in worms and TRIM32 in mice, as positive regulators of microRNA function.

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Keywords

Basic Helix-Loop-Helix Proteins, Mice, MicroRNAs, Biochemistry, Genetics and Molecular Biology(all), Ubiquitin-Protein Ligases, Animals, Caenorhabditis elegans

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
36
Top 10%
Top 10%
Top 10%
hybrid
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