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Cell
Article
License: Elsevier Non-Commercial
Data sources: UnpayWall
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Cell
Article . 2008
License: Elsevier Non-Commercial
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Cell
Article . 2008 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
MPG.PuRe
Article . 2008
Data sources: MPG.PuRe
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Mitofusin 2 Builds a Bridge between ER and Mitochondria

Authors: Merkwirth, C.; Langer, T.;

Mitofusin 2 Builds a Bridge between ER and Mitochondria

Abstract

Mutations in mitofusin 2 (MFN2), a dynamin-like GTPase required for mitochondrial fusion, cause the peripheral neuropathy Charcot-Marie-Tooth type 2A. In a recent report in Nature, de Brito and Scorrano (2008) demonstrate a new function of MFN2-tethering the endoplasmic reticulum and mitochondria to control the efficiency of mitochondrial uptake of Ca2+ ions.

Keywords

Mice, Purkinje Cells, Biochemistry, Genetics and Molecular Biology(all), Animals, Endoplasmic Reticulum, Axonal Transport, Cell Line, GTP Phosphohydrolases, Mitochondria

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    115
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
115
Top 10%
Top 10%
Top 10%
hybrid