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Cell
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License: Elsevier Non-Commercial
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SnapShot: Vertebrate Transposons

Authors: Mandal, Prabhat K.; Kazazian, Haig H.;

SnapShot: Vertebrate Transposons

Abstract

Transposable elements, originally discovered in maize by Barbara McClintock, are discrete DNA segments that can insert into new chromosomal locations either by a “cut and paste” or by a “copy and paste” mechanism. Transposable elements are involved in a wide variety of biological transactions including genome alteration by element insertion or deletion and homologous recombination between element copies. They fall into two classes according to whether their transposition intermediate is RNA (class 1 or retrotransposons) or DNA (class 2 or DNA-based transposons). Recent genome sequencing projects have revealed that transposable elements make up a major portion of most vertebrate genomes. For example, transposable elements account for almost 50% of the human genome. This table summarizes different types of transposable element content in human, mouse, opossum, platypus, chicken, and fugu.

Related Organizations
Keywords

Genome, Biochemistry, Genetics and Molecular Biology(all), Genome, Human, Vertebrates, DNA Transposable Elements, Animals, Humans

  • BIP!
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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    69
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
69
Top 10%
Top 10%
Top 10%
hybrid