Caspase-1 Builds a New Barrier to Infection
Copyright policy )Caspase-1 Builds a New Barrier to Infection
Caspase-1 promotes both the maturation of proinflammatory cytokines and apoptosis in cells infected by certain pathogens. Work by now reveals a surprising new function for caspase-1: the stimulation of membrane biogenesis to repair damage caused by bacterial pore-forming toxins. Thus, caspase-1 may promote host cell survival as a means of resistance to pathogenic bacteria.
- McGill University Canada
Sterol Regulatory Element Binding Proteins, Biochemistry, Genetics and Molecular Biology(all), Cell Survival, Bacterial Toxins, Caspase 1, Cell Membrane, Bacterial Infections, Immunity, Innate, Membrane Lipids, Animals, Humans, Signal Transduction
Sterol Regulatory Element Binding Proteins, Biochemistry, Genetics and Molecular Biology(all), Cell Survival, Bacterial Toxins, Caspase 1, Cell Membrane, Bacterial Infections, Immunity, Innate, Membrane Lipids, Animals, Humans, Signal Transduction
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