ZOning out Tight Junctions
Copyright policy )ZOning out Tight Junctions
The tight junction is an intricate seal between adjoining epithelial cells that also separates the apical and basolateral membranes within these cells. A paper in this issue of Cell by Umeda et al. (2006) demonstrates that loss of the ZO scaffolding proteins prevents the formation of tight junctions but surprisingly does not perturb apico-basal polarity.
- University of Michigan–Flint United States
- Pohang University of Science and Technology Korea (Republic of)
- University of Michigan–Ann Arbor United States
Biochemistry, Genetics and Molecular Biology(all), Cell Polarity, Membrane Proteins, Epithelial Cells, Phosphoproteins, Tight Junctions, Mice, Zonula Occludens-1 Protein, Animals, Protein Isoforms, RNA, Small Interfering
Biochemistry, Genetics and Molecular Biology(all), Cell Polarity, Membrane Proteins, Epithelial Cells, Phosphoproteins, Tight Junctions, Mice, Zonula Occludens-1 Protein, Animals, Protein Isoforms, RNA, Small Interfering
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