OPA1 and PARL Keep a Lid on Apoptosis
Copyright policy )OPA1 and PARL Keep a Lid on Apoptosis
A change in the shape of mitochondrial cristae must take place to attain rapid and complete release of cytochrome c during apoptosis. In this issue of Cell, Cipolat et al. and Frezza et al. (2006) show that a rhomboid intramembrane protease PARL and a dynamin-related protein OPA1 are critical regulators of cristae remodeling.
- Cancer Research UK United Kingdom
- Cancer Research UK Scotland Institute United Kingdom
Biochemistry, Genetics and Molecular Biology(all), Cytochromes c, Apoptosis, GTP Phosphohydrolases, Mitochondria, Mitochondrial Proteins, Caspases, Mitochondrial Membranes, Metalloproteases, Animals, Humans, Signal Transduction
Biochemistry, Genetics and Molecular Biology(all), Cytochromes c, Apoptosis, GTP Phosphohydrolases, Mitochondria, Mitochondrial Proteins, Caspases, Mitochondrial Membranes, Metalloproteases, Animals, Humans, Signal Transduction
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).52 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!