P-Bodies React to Stress and Nonsense
Copyright policy )P-Bodies React to Stress and Nonsense
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
- The University of Texas MD Anderson Cancer Center United States
Saccharomyces cerevisiae Proteins, Biochemistry, Genetics and Molecular Biology(all), RNA Stability, RNA-Binding Proteins, RNA Transport, MicroRNAs, Codon, Nonsense, Cell Line, Tumor, Protein Biosynthesis, Trans-Activators, Cytoplasmic Structures, Humans, RNA, Messenger, 3' Untranslated Regions, RNA Helicases, Adaptor Proteins, Signal Transducing, Cationic Amino Acid Transporter 1, Protein Binding
Saccharomyces cerevisiae Proteins, Biochemistry, Genetics and Molecular Biology(all), RNA Stability, RNA-Binding Proteins, RNA Transport, MicroRNAs, Codon, Nonsense, Cell Line, Tumor, Protein Biosynthesis, Trans-Activators, Cytoplasmic Structures, Humans, RNA, Messenger, 3' Untranslated Regions, RNA Helicases, Adaptor Proteins, Signal Transducing, Cationic Amino Acid Transporter 1, Protein Binding
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