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Intraflagellar Transport and Cilium-Based Signaling

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2006 English Publisher:Elsevier BVJournal:Cell, volume 125, pages 439-442 (issn: 0092-8674, Copyright policy )
Authors: Scholey, Jonathan M.; Anderson, Kathryn V.;

doi: 10.1016/j.cell.2006.04.013

pmid: 16678091

Intraflagellar Transport and Cilium-Based Signaling

Abstract

Cilia are specialized structures that not only play diverse roles in cell motility but also transmit signals to the cytoplasm and nucleus to control gene expression, cell function, animal development, and behavior. Cilia are assembled and maintained by the intraflagellar transport (IFT) machinery, which coordinates rapid, bidirectional transport between the cell body and the distal tip of the cilium. A new study (Wang et al., 2006) illuminates the role of IFT in cilium-based signaling during mating in the alga Chlamydomonas.

Related Organizations
Keywords

Biochemistry, Genetics and Molecular Biology(all), Molecular Motor Proteins, Chlamydomonas, Cell Polarity, Protein Transport, Sexual Behavior, Animal, Flagella, Trans-Activators, Animals, Hedgehog Proteins, Cilia, Body Patterning, Signal Transduction

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 192
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
192
Top 10%
Top 1%
Top 1%
hybrid