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Cell Calcium
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Cell Calcium
Article . 2011 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
https://pubmed.ncbi.nlm.nih.go...
Article . 2011
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.c...
Article
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L-type calcium channel auto-regulation of transcription

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2011 English Publisher:Elsevier BVJournal:Cell Calcium, volume 49, pages 306-313 (issn: 0143-4160, Copyright policy )
Authors: Jonathan, Satin; Elizabeth A, Schroder; Shawn M, Crump;

doi: 10.1016/j.ceca.2011.01.001

pmid: 21295347

pmc: PMC3097264

L-type calcium channel auto-regulation of transcription

Abstract

L-type calcium channels (LTCC) impact the function of nearly all excitable cells. The classical LTCC function is to mediate trans-sarcolemmal Ca(2+) flux. This review focuses on the contribution of a mobile segment of the LTCC that regulates ion channel function, and also serves as a regulator of transcription in the nucleus. Specifically we highlight recent work demonstrating an auto-feedback regulatory pathway whereby the LTCC transcription factor regulates the LTCC. Also discussed is acute and long-term regulation of function by the LTCC-transcription regulator.

Related Organizations
Keywords

Cell Nucleus, Calcium Channels, L-Type, Gene Expression Regulation, Transcription, Genetic, Humans, Calcium, Myocytes, Cardiac, Promoter Regions, Genetic, Protein Structure, Tertiary

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
34
Top 10%
Top 10%
Top 10%
bronze