Although the accuracy of direct digitization of oral structure has been improved, indirect digitization is still required in specific situations such as full-arch scanning. Once accurate images are imported, efficient designing can be achieved by CAD software. Although smile design using a 3-dimensional facial scan better predicts planned restorations, further improvement in virtual articulators is needed for complex cases. Computer-aided manufacturing can be offered in several formats such as chairside, laboratory, or centralized fabrications. The subtractive technique is mainly used for restorations, and many chairside CAM materials are available now, but the additive technique has the potential to save materials and an advantage in fabricating complex geometries. Limited evidence is available in applying CAD/CAM technologies in implant restorations. However, it is used to fabricate custom implant abutments and crowns from various materials such as titanium, zirconia, and PEEK and hybrid crowns using stock titanium base abutments.