Biological Molecules for the Regeneration of the Pulp-Dentin Complex

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2017 English Publisher:Elsevier BVJournal:Dental Clinics of North America, volume 61, pages 127-141 (issn: 0011-8532,

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Authors: Sahng G, Kim;

doi: 10.1016/j.cden.2016.08.005

pmid: 27912814

Biological Molecules for the Regeneration of the Pulp-Dentin Complex

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Abstract

Regenerative endodontic treatment has yielded excellent clinical outcomes, but only several animal studies have shown the robust regeneration of the pulp-dentin complex. The biological molecules, if properly delivered, can enkindle regeneration of dental pulp and dentin rather than repair with tissues of periodontal origin. This review details the biological significance of regenerating the pulp-dentin complex, the effects of biological cues in pulp regeneration, and the delivery strategies of biological molecules to enhance the outcomes of regenerative endodontic therapy.

Related Organizations

Columbia University, USA
United States
King’s University
United States

Keywords

Biological Factors, Dentin, Animals, Humans, Regeneration, Dental Pulp

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