Ventilator-induced Lung Injury
Copyright policy )Ventilator-induced Lung Injury
Prevention of ventilator-induced lung injury (VILI) can attenuate multiorgan failure and improve survival in at-risk patients. Clinically significant VILI occurs from volutrauma, barotrauma, atelectrauma, biotrauma, and shear strain. Differences in regional mechanics are important in VILI pathogenesis. Several interventions are available to protect against VILI. However, most patients at risk of lung injury do not develop VILI. VILI occurs most readily in patients with concomitant physiologic insults. VILI prevention strategies must balance risk of lung injury with untoward side effects from the preventive effort, and may be most effective when targeted to subsets of patients at increased risk.
- University of California, San Francisco United States
- Massachusetts General Hospital United States
- University of California, San Diego United States
- University of California, San Diego United States
- Harvard University United States
Respiratory mechanics, Ventilator-Induced Lung Injury, Clinical Sciences, Respiratory System, 610, Clinical sciences, Cardiovascular medicine and haematology, 618, Rare Diseases, Mechanical ventilation, Clinical Research, Acute lung injury, 2.1 Biological and endogenous factors, Humans, Lung, Acute Respiratory Distress Syndrome, Ventilator-induced lung injury, Respiratory Distress Syndrome, Biomedical and Clinical Sciences, Acute respiratory distress syndrome, Prevention, Lung Injury, Respiratory, Respiratory Mechanics, Patient Safety
Respiratory mechanics, Ventilator-Induced Lung Injury, Clinical Sciences, Respiratory System, 610, Clinical sciences, Cardiovascular medicine and haematology, 618, Rare Diseases, Mechanical ventilation, Clinical Research, Acute lung injury, 2.1 Biological and endogenous factors, Humans, Lung, Acute Respiratory Distress Syndrome, Ventilator-induced lung injury, Respiratory Distress Syndrome, Biomedical and Clinical Sciences, Acute respiratory distress syndrome, Prevention, Lung Injury, Respiratory, Respiratory Mechanics, Patient Safety
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