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SnapShot: Immune Checkpoint Inhibitors

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2017 United States English Publisher:Elsevier BVJournal:Cancer Cell, volume 31, pages 848-8,480 (issn: 1535-6108, Copyright policy )
Authors: Abril-Rodriguez, Gabriel; Ribas, Antoni;

doi: 10.1016/j.ccell.2017.05.010

pmid: 28609660

SnapShot: Immune Checkpoint Inhibitors

Abstract

Immunotherapy has changed the landscape of cancer treatment. Checkpoint blockade therapies unleash breaks in the immune system and induce long-lasting responses. However, a significant number of patients do not respond (innate resistance), and a subset progress after responding (acquired resistance). A better understanding of the molecular mechanisms underlying checkpoint blockade therapies will facilitate the design of novel strategies to treat and prevent resistance. To view this SnapShot, open or download the PDF.

Country
United States
Related Organizations
Keywords

Prevention, Oncology and Carcinogenesis, Drug Resistance, Neurosciences, Cell Cycle Checkpoints, Adaptive Immunity, Vaccine Related, Good Health and Well Being, Clinical Research, 5.1 Pharmaceuticals, Drug Resistance, Neoplasm, Neoplasms, Neoplasm, Humans, Immunization, Oncology & Carcinogenesis, Immunotherapy, Interferons, Development of treatments and therapeutic interventions, Cancer

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 266
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
266
Top 0.1%
Top 10%
Top 1%
Green
hybrid
Related to Research communities
Knowmad Institut
Cancer Research