Interfering with CCL5/CCR5 at the Tumor-Stroma Interface
Copyright policy )Interfering with CCL5/CCR5 at the Tumor-Stroma Interface
In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.
Colorectal Neoplasms; Humans; Soft Tissue Neoplasms; Chemokine CCL5; Receptors, CCR5; Oncology; Cell Biology; Cancer Research, Receptors, CCR5, Humans, Soft Tissue Neoplasms, Colorectal Neoplasms; Humans; Soft Tissue Neoplasms; Chemokine CCL5; Receptors, CCR5, Colorectal Neoplasms, Chemokine CCL5
Colorectal Neoplasms; Humans; Soft Tissue Neoplasms; Chemokine CCL5; Receptors, CCR5; Oncology; Cell Biology; Cancer Research, Receptors, CCR5, Humans, Soft Tissue Neoplasms, Colorectal Neoplasms; Humans; Soft Tissue Neoplasms; Chemokine CCL5; Receptors, CCR5, Colorectal Neoplasms, Chemokine CCL5
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