Biomarkers in Sepsis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2018 Netherlands English Publisher:Elsevier BVJournal:Critical Care Clinics, volume 34, pages 139-152 (issn: 0749-0704,

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Authors: van Engelen, Tjitske S. R.; Wiersinga, Willem Joost; Scicluna, Brendon P.; van der Poll, Tom;

doi: 10.1016/j.ccc.2017.08.010

pmid: 29149935

Biomarkers in Sepsis

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Abstract

A biomarker is a characteristic by which a (patho)physiologic process can be identified. Biomarkers can be of diagnostic value (to discriminate infection from noninfectious conditions or to determine the causative pathogen), of prognostic value (assigning risk profiles and predict outcome), and in the future may be of theranostic value (aid in selection and monitoring of therapy). Systems biology provides a promising tool for the discovery of novel biomarkers. Biomarkers can be the key to personalized targeted treatment in the future clinical management of sepsis.

Country

Netherlands

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Keywords

Sepsis, Humans, Proteins, RNA, Biomarkers

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