Effects of clonazepam on self-induced photoparoxysmal responses
Copyright policy )Effects of clonazepam on self-induced photoparoxysmal responses
A 5-year-old girl exhibited daily episodes of repetitive blinking lasting 5-10 s. Electroencephalography (EEG) revealed marked photoparoxysmal responses (PPR) at 3-20 Hz of photic stimulation and diffuse spike-wave bursts during sleep. A 24-h video EEG identified 11 episodes of repetitive blinking, 3 of which resulted in widespread spike-wave discharges. These suggested that the behavior of the patient represented self-induction of PPR. Valproate sodium was ineffective in decreasing PPR, as revealed by EEG, and the frequency of blinking episodes, but clonazepam attenuated PPR and significantly decreased the blinking behavior.
Blinking, Valproic Acid, Brain, Electroencephalography, Clonazepam, Treatment Outcome, Child, Preschool, Humans, Anticonvulsants, Female, Photosensitivity Disorders, Sleep, Photic Stimulation
Blinking, Valproic Acid, Brain, Electroencephalography, Clonazepam, Treatment Outcome, Child, Preschool, Humans, Anticonvulsants, Female, Photosensitivity Disorders, Sleep, Photic Stimulation
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