Point A vs. HR-CTV D90 in MRI-based cervical brachytherapy of small and large lesions
Copyright policy )Point A vs. HR-CTV D90 in MRI-based cervical brachytherapy of small and large lesions
To evaluate the dosimetric benefits of MRI-based brachytherapy in small and large high-risk clinical target volume (HR-CTV) in cervical cancer.Twenty-eight fractions obtained from sixteen cervical cancer patients treated with MRI-based high-dose-rate brachytherapy with standard tandem and ovoid applicators were used; original fractions were optimized to HR-CTV D90. Fractions were separated based on the median volume into small and large (HR-CTV 25 cm3) lesion groups. Retrospective plans prescribed to Point A were created for each fraction. D0.1 cc, D2 cc, and International Commission of Radiation Unit and Measurements (ICRU) points were used to compare Point A vs. HR-CTV D90 plans for bladder, rectum, and sigmoid.In the small lesion group, Point A plans vs. HR-CTV D90 plans had significantly higher D0.1 cc, D2 cc, and ICRU points for bladder, rectum, and sigmoid (p 25 cm3. Incorporation of interstitial needles for patients with larger HR-CTV is likely the best method to decrease dose to OARs and improve tumor coverage.
- Loyola University Chicago United States
Organs at Risk, Radiotherapy Planning, Computer-Assisted, Brachytherapy, Urinary Bladder, Rectum, Uterine Cervical Neoplasms, Radiotherapy Dosage, Magnetic Resonance Imaging, Colon, Sigmoid, Humans, Female, Aged, Retrospective Studies
Organs at Risk, Radiotherapy Planning, Computer-Assisted, Brachytherapy, Urinary Bladder, Rectum, Uterine Cervical Neoplasms, Radiotherapy Dosage, Magnetic Resonance Imaging, Colon, Sigmoid, Humans, Female, Aged, Retrospective Studies
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