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Biophysical Journal
Article
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Biophysical Journal
Article . 2013
License: Elsevier Non-Commercial
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Biophysical Journal
Article . 2013 . Peer-reviewed
License: Elsevier Non-Commercial
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Size Specific Trapping at a Convergent Stagnation Point

Authors: Jennifer Kreft Pearce; Sarah Jeanfavre;

Size Specific Trapping at a Convergent Stagnation Point

Abstract

DNA has been observed to be trapped at a convergent stagnation point created by opposite rotating vortices in simulations based on the lattice-Boltzmann method using a bead-spring model for the DNA. Previous work has successfully separated polymers whose length differs by a factor of 2. However more precise separation based on length could potentially be achieved. Preliminary simulations have trapped 60% of the smaller strands in polymers length ratio 1.5:1. Mastering this technique could allow advancements in developing microfluidic techniques for DNA amplification based on PCR and purification of the PCR product. Additionally these simulations mimic conditions found in pores of hydrothermal vents, giving hypothesis on the development of life.

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Biophysics

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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