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DNA has been observed to be trapped at a convergent stagnation point created by opposite rotating vortices in simulations based on the lattice-Boltzmann method using a bead-spring model for the DNA. Previous work has successfully separated polymers whose length differs by a factor of 2. However more precise separation based on length could potentially be achieved. Preliminary simulations have trapped 60% of the smaller strands in polymers length ratio 1.5:1. Mastering this technique could allow advancements in developing microfluidic techniques for DNA amplification based on PCR and purification of the PCR product. Additionally these simulations mimic conditions found in pores of hydrothermal vents, giving hypothesis on the development of life.
Biophysics
Biophysics
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