Photochemical transformation of a cellulose biosynthesis inhibitor into phytoene desaturase inhibitors
Copyright policy )Photochemical transformation of a cellulose biosynthesis inhibitor into phytoene desaturase inhibitors
Mode of action studies showed that 5-methyl-N,N-bis[6-(trifluoromethyl)pyridin-3-yl]pyridin-2-amine (4), a representative from a new class of herbicidal tris-pyridyl amines, is an inhibitor of cellulose biosynthesis (CB). The compound undergoes an oxidative photocyclization, when exposed to UV-B light (300-340 nm) in the presence of oxygen, to give a new class of herbicidal pyrrolodipyridines. These compounds are potent inhibitors of the herbicide target enzyme phytoene desaturase and no longer inhibit CB.
- Bayer Germany
- Bayer (Germany) Germany
Nicotiana, Molecular Structure, Herbicides, Pyridines, Ultraviolet Rays, Photochemical Processes, Pyridazines, Drug Design, Brassicaceae, Cellulose, Oxidoreductases, Cells, Cultured
Nicotiana, Molecular Structure, Herbicides, Pyridines, Ultraviolet Rays, Photochemical Processes, Pyridazines, Drug Design, Brassicaceae, Cellulose, Oxidoreductases, Cells, Cultured
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