descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Feb 2005 English Publisher:Elsevier BVJournal:Bioorganic & Medicinal Chemistry Letters, volume 15, pages 1,131-1,133 (issn: 0960-894X,

Authors: Gilles, Tamagnan; David, Alagille; Xing, Fu; Nora S, Kula; Ross J, Baldessarini; Robert B, Innis; Ronald M, Baldwin;

doi: 10.1016/j.bmcl.2004.12.014 , 10.1002/chin.200527194

pmid: 15686927

Synthesis and monoamine transporter affinity of new 2β-carbomethoxy-3β-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency

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Abstract

AbstractFor Abstract see ChemInform Abstract in Full Text.

Related Organizations

University of Connecticut
United States
Institute for Neurodegenerative Disorders
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Temple University
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Yale University
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Keywords

Cerebral Cortex, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Membrane Glycoproteins, Norepinephrine Plasma Membrane Transport Proteins, Dose-Response Relationship, Drug, Symporters, Membrane Transport Proteins, Nerve Tissue Proteins, Rats, Structure-Activity Relationship, Animals, Selective Serotonin Reuptake Inhibitors, Tropanes

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BindingDB Entry 50037423: Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.
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