Synthesis and antioxidant ability of 6,6′-diamino-6,6′-dideoxytrehalose

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2017 English Publisher:Elsevier BVJournal:Bioorganic Chemistry, volume 74, pages 66-71 (issn: 0045-2068,

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Authors: Wenqiang, Tan; Qing, Li; Tingting, Zhou; Qiuhong, Chen; Gang, Wang; Fang, Dong; Zhanyong, Guo;

doi: 10.1016/j.bioorg.2017.07.005

pmid: 28755563

Synthesis and antioxidant ability of 6,6′-diamino-6,6′-dideoxytrehalose

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Abstract

In order to study the influence of amino group on antioxidant activity of oligosaccharides, an amino disaccharide, 6,6'-diamino-6,6'-dideoxytrehalose (DAMDT) was successfully prepared in this paper, and its antioxidant activities against DPPH, superoxide, hydrogen peroxide, and hydroxyl radicals, and reducing power were evaluated, respectively. The results indicated that DAMDT had better antioxidant activity than trehalose at any tested concentration. The influence of amino group on antioxidant activity of disaccharides is positive based on the results in this paper, and amination should be an effective method to improve the bioactivity of saccharides.

Related Organizations

Chinese Academy of Sciences
China (People's Republic of)
Yantai Institute of Coastal Zone Research
China (People's Republic of)
University of Chinese Academy of Sciences
China (People's Republic of)

Keywords

Picrates, Hydroxyl Radical, Superoxides, Biphenyl Compounds, Trehalose, Hydrogen Peroxide, Antioxidants

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