Genetics of spondyloarthritis
Copyright policy )Genetics of spondyloarthritis
This chapter reviews evidence from family and twin studies supporting the strong genetic predisposition of the spondyloarthritides (SpA), which is only partially attributable to the major histocompatibility locus. The current concept of SpA heterogeneity has been challenged by family studies which showed that all articular and extra-articular manifestations were linked together, and most likely to the same genetic factors.
- Assistance Publique -Hopitaux De Paris France
- Hôpital Cochin France
- Institut Cochin France
- Hôpital Ambroise-Paré France
- French Institute of Health and Medical Research France
Family Health, Male, Molecular Epidemiology, Major Histocompatibility Complex, Disease Models, Animal, Spondylarthritis, Animals, Humans, Twin Studies as Topic, Female, Genetic Predisposition to Disease, Spondylitis, Ankylosing, France
Family Health, Male, Molecular Epidemiology, Major Histocompatibility Complex, Disease Models, Animal, Spondylarthritis, Animals, Humans, Twin Studies as Topic, Female, Genetic Predisposition to Disease, Spondylitis, Ankylosing, France
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