Structure and function of poly(A) binding proteins
Copyright policy )Structure and function of poly(A) binding proteins
Poly (A) tails are found at the 3' ends of almost all eukaryotic mRNAs. They are bound by two different poly (A) binding proteins, PABPC in the cytoplasm and PABPN1 in the nucleus. PABPC functions in the initiation of translation and in the regulation of mRNA decay. In both functions, an interaction with the m7G cap at the 5' end of the message plays an important role. PABPN1 is involved in the synthesis of poly (A) tails, increasing the processivity of poly (A) polymerase and contributing to defining the length of a newly synthesized poly (A) tail.
Cell Nucleus, Cytoplasm, Temperature, Models, Biological, Poly(A)-Binding Protein I, Poly(A)-Binding Protein II, Poly(A)-Binding Proteins, Fungal Proteins, Structure-Activity Relationship, Animals, Humans, RNA, Messenger, Protein Binding
Cell Nucleus, Cytoplasm, Temperature, Models, Biological, Poly(A)-Binding Protein I, Poly(A)-Binding Protein II, Poly(A)-Binding Proteins, Fungal Proteins, Structure-Activity Relationship, Animals, Humans, RNA, Messenger, Protein Binding
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).300 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 1% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!