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Atherosclerosis
Article
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Atherosclerosis
Article . 2021 . Peer-reviewed
License: Elsevier TDM
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Reviewing imaging modalities for the assessment of plaque erosion

Authors: Carlos Collet; Edoardo Conte; Saima Mushtaq; Sofie Brouwers; Toshiro Shinke; Ahmet Umit Coskun; Zhongyue Pu; +3 Authors

Reviewing imaging modalities for the assessment of plaque erosion

Abstract

Plaque rupture followed by intracoronary thrombus formation is recognized as the most common pathophysiological mechanism in acute coronary syndromes (ACS). The second most common underlying substrate for ACS is plaque erosion whose hallmark is thrombus formation without cap disruption. Invasive and non-invasive methods have emerged as a promising tool for evaluation of plaque features that either predict or detect plaque erosion. Optical coherence tomography (OCT), high-definition intravascular ultrasound (IVUS), near-infrared spectroscopy (NIRS), and near-infrared autofluorescence (NIRF) have been used to study plaque erosion. The detection of plaque erosion in the clinical setting, mainly facilitated by OCT, has shed light upon the complex pathophysiology underlying ACS not related to plaque rupture. Coronary computed tomography angiography (CCTA), which is to date the most commonly used non-invasive technique for coronary plaque evaluation, may also have a role in the evaluation of patients predisposed to erosion. Also, computational models enabling quantification of endothelial shear stress may pave the way to new research in coronary plaque pathophysiology. This review focuses on the recent imaging techniques for the evaluation of plaque erosion including invasive and non-invasive assessment.

Countries
Italy, Belgium
Keywords

Spectroscopy, Near-Infrared, Computed Tomography Angiography, Coronary computed tomography; Intravascular ultrasound; Optical computed tomography; Plaque erosion, Coronary Vessels/diagnostic imaging, Coronary Artery Disease, Coronary Angiography, Coronary Vessels, Plaque, Atherosclerotic, Acute Coronary Syndrome/diagnostic imaging, Humans, Plaque, Atherosclerotic/diagnostic imaging, Acute Coronary Syndrome, computed tomography angiography, Tomography, Optical Coherence, Ultrasonography, Interventional, Coronary Artery Disease/diagnostic imaging

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    14
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
14
Top 10%
Average
Top 10%
Green
bronze