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Eosinophilic esophagitis

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2014 English Publisher:Elsevier BVJournal:Annals of Allergy, Asthma & Immunology, volume 112, pages 397-403 (issn: 1081-1206,

Authors: Jamie, Merves; Amanda, Muir; Prasanna, Modayur Chandramouleeswaran; Antonella, Cianferoni; Mei-Lun, Wang; Jonathan M, Spergel;

doi: 10.1016/j.anai.2014.01.023

pmid: 24566295

pmc: PMC4332835

Eosinophilic esophagitis

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Abstract

To review the understanding of the pathogenesis of eosinophilic esophagitis (EoE) and the role of the immune system in the disease process.Peer-reviewed articles on EoE from PubMed searching for "Eosinophilic Esophagitis and fibrosis" in the period of 1995 to 2013.Studies on the clinical and immunologic features, pathogenesis, and management of EoE.Recent work has revealed that thymic stromal lymphopoietin and basophil have an increased role in the pathogenesis of disease. Additional understanding on the role of fibrosis in EoE is emerging.The incidence of EoE is increasing like most atopic disease. Similar to other allergic diseases, EoE is treated with topical steroids and/or allergen avoidance.

Related Organizations

University of Pennsylvania
United States
Children's Hospital of Philadelphia
United States

Keywords

Adult, Male, Eosinophilic Esophagitis, Allergens, Basophils, Eosinophils, Esophagus, Thymic Stromal Lymphopoietin, Adrenal Cortex Hormones, Cytokines, Humans, Female, Genetic Predisposition to Disease, Lymphocytes, Child

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	36
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%