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Publication . Article . 2006

Lymphocytic choriomeningitis virus: An emerging obstetric pathogen?

Denise J. Jamieson; Athena P. Kourtis; Michael Bell; Sonja A. Rasmussen;
Open Access  
Published: 01 Jun 2006 Journal: American Journal of Obstetrics and Gynecology, volume 194, pages 1,532-1,536 (issn: 0002-9378, Copyright policy )
Publisher: Elsevier BV
Abstract
A report in May 2005 from the Centers for Disease Control and Prevention describing a cluster of lymphocytic choriomeningitis virus (LCMV) infections among 4 solid organ recipients has increased awareness of and clinical interest in this pathogen. Human infection with LCMV results from direct or indirect contact with rodents. LCMV has particular relevance to obstetrics, as it is likely an under-recognized abortifacient and fetal teratogen. There have been 54 cases of congenital LCMV reported since 1955, with 34 of the cases diagnosed since 1993. Chorioretinitis and hydrocephalus are the predominant characteristics among children diagnosed with congenital LCMV infection. Obstetricians should educate their pregnant patients about the risks of exposure to laboratory, pet, and wild rodents.
Subjects by Vocabulary

Microsoft Academic Graph classification: Hydrocephalus medicine.disease medicine business.industry business Arenavirus biology.organism_classification biology Immunology Virology Teratology Virus Pregnancy Chorioretinitis Pathogen Lymphocytic choriomeningitis

Medical Subject Headings: viruses virus diseases nervous system diseases

Subjects

Obstetrics and Gynecology