Antiplatelet drug nonresponsiveness

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2008 English Publisher:Elsevier BVJournal:American Heart Journal, volume 155, pages 591-599 (issn: 0002-8703,

Copyright policy )

Authors: Patrick, Gladding; Mark, Webster; John, Ormiston; Sarah, Olsen; Harvey, White;

doi: 10.1016/j.ahj.2007.12.034

pmid: 18371464

Antiplatelet drug nonresponsiveness

- Summary
- Subjects
- Metrics

Abstract

The response to most medication, including antiplatelet drugs, is highly variable between individuals. Observational studies have shown that nonresponders to antiplatelet agents appear to have an increased incidence of vascular events. This review article reviews the background, mechanisms, and evidence in support of the clinical significance of this phenomenon.

Related Organizations

Auckland District Health Board
New Zealand
Auckland City Hospital
New Zealand

Keywords

Ticlopidine, Aspirin, Platelet Function Tests, Drug Resistance, Humans, Coronary Disease, Acute Coronary Syndrome, Platelet Aggregation Inhibitors, Clopidogrel

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	53
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%