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Neurotrophin-3 modulates synaptic transmission

Name: Neurotrophin-3 modulates synaptic transmission
Creator: Elizabeth Hernández-Echeagaray
Keywords: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Gene Expression Regulation, Neurotrophin 3, Animals, Humans, Receptor, trkC, Synaptic Transmission, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 01 Jan 2020Publisher:Elsevier BV

Authors: Elizabeth Hernández-Echeagaray;

doi: 10.1016/bs.vh.2020.04.008

pmid: 32723551

Neurotrophin-3 modulates synaptic transmission

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Abstract

Neurotrophin-3 (NT-3) belongs to a family of growth factors called neurotrophins whose actions are centered in the nervous system. NT-3 is structurally related to other neurotrophins like brain-derived neurotrophic factor. The expression of NT-3 starts with the onset of neurogenesis and continues throughout life. A wealth of information links NT-3 to the growth, differentiation, and survival of hippocampal cells as well as sympathetic and sensory neurons. These studies have described the distribution of NT-3 and its receptors throughout development and in the mature nervous system. Prior works has begun to cell-type specific impact of NT-3 as well as identify the signaling pathways involved. However, much less is known about how NT-3 regulates synaptic transmission. This chapter focuses role of NT-3 in the modulation of synaptic transmission.

Related Organizations

National Autonomous University of Mexico
Mexico

Keywords

Gene Expression Regulation, Neurotrophin 3, Animals, Humans, Receptor, trkC, Synaptic Transmission

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	27
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%