Cognitive reserve is a latent construct theorized to account for the discrepancy between observed brain deterioration and ultimate clinical outcomes. This review outlines the theoretical development of the reserve concept and presents major trends within epidemiological and neuroimaging research literatures in support of such a construct. Particular focus is placed on the implications for cognitive aging and dementia.

Related Organizations

King’s University
United States
University Physicians
United States

Keywords

Aged, 80 and over, Male, Cognitive Reserve, Cognitive Aging, Humans, Cognitive Dysfunction, Dementia, Female, Aged

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