Abstract Schizophrenia includes positive symptoms (hallucinations, delusions), but also negative/affective symptoms such as affective blunting, avolition, and anhedonia. In recent years, many animal models of schizophrenia have been designed, including models based on administration of pharmacological agents (such as phencyclidine or amphetamine), on genetic or developmental manipulations (ventral hippocampus lesions, administration of antimitotics during gestation). Most of them enabled the detection of positive symptoms of schizophrenia. However, and this is less well-known, some of them also enabled the detection of negative and/or affective symptoms such as anhedonia. This confers higher relevance to these models because they are sensitive to both kinds of symptomatic features. Incorporating phenotyping of affective symptoms in animal models of schizophrenia will facilitate the design of new treatments effective in improving not only positive symptoms, but also negative/affective ones.