<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Growth factors and receptors in cancer

Name: Growth factors and receptors in cancer
Creator: Adrian L. Harris
Keywords: Gene Expression Regulation, Neoplastic, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Neoplasms, Animals, Humans, Receptors, Cell Surface, Oncogenes, Growth Substances

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1991Publisher:Elsevier BVJournal:Current Opinion in Biotechnology, volume 2, pages 260-268 (issn: 0958-1669,

Authors: Adrian L. Harris;

doi: 10.1016/0958-1669(91)90019-2

pmid: 1369356

Growth factors and receptors in cancer

- Summary
- Subjects
- Metrics

Abstract

There have been a number of recent developments in mechanisms of action of growth factors and their receptors with particular relevance to cancer. The tyrosine kinase receptor family, in particular, has been shown to be important in tumour growth. These receptors are the products of oncogenes, or can interact with other oncogene pathways. Thus, antibodies to either the receptor or its ligand can be used as therapeutic agents. Peptide analogues of ligands that can block receptor activation are also potential therapeutic agents.

Related Organizations

University of Oxford
United Kingdom
Oxford University Hospitals NHS Trust
United Kingdom
John Radcliffe Hospital
United Kingdom

Keywords

Gene Expression Regulation, Neoplastic, Neoplasms, Animals, Humans, Receptors, Cell Surface, Oncogenes, Growth Substances, Prognosis, Signal Transduction

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average