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Heterogeneity of hematopoietic stem cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1993Publisher:Elsevier BVJournal:Current Opinion in Immunology, volume 5, pages 177-184 (issn: 0952-7915,

Authors: Eytan J. Alpern; Irving L. Weissman; Nobuko Uchida; William H. Fleming;

doi: 10.1016/0952-7915(93)90002-a

pmid: 8099486

Heterogeneity of hematopoietic stem cells

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Abstract

Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.

Related Organizations

Stanford University
United States

Keywords

Gene Rearrangement, Membrane Glycoproteins, Hematopoietic System, Cell Differentiation, Mice, Inbred Strains, Hematopoietic Stem Cells, Antigens, Differentiation, Hematopoiesis, Immunophenotyping, Mice, Antigens, Surface, Animals, Thy-1 Antigens

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	140
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%