
pmid: 8302915
PGs and probably other eicosanoids play a fundamental role in the process of ovulation, more specifically in the mechanism of follicle wall rupture. Although the nature of this role has yet to be established a number of plausible theories exist. It seems likely that altered PG metabolism is responsible for some cases of human female subfertility. The potential for fertility control by PG inhibition is an exciting possibility for the future.
Mammals, Ovulation, Hypothalamo-Hypophyseal System, Prostaglandin Antagonists, Anti-Inflammatory Agents, Non-Steroidal, Indomethacin, Muscle, Smooth, Rats, Ovarian Follicle, Gonadotropins, Pituitary, Animals, Eicosanoids, Humans, Female, Rabbits, Reactive Oxygen Species, Muscle Contraction
Mammals, Ovulation, Hypothalamo-Hypophyseal System, Prostaglandin Antagonists, Anti-Inflammatory Agents, Non-Steroidal, Indomethacin, Muscle, Smooth, Rats, Ovarian Follicle, Gonadotropins, Pituitary, Animals, Eicosanoids, Humans, Female, Rabbits, Reactive Oxygen Species, Muscle Contraction
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