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Genomics
Article . 1988 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Genomics
Article . 1989
Data sources: Europe PubMed Central
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Genomics
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Molecular and genetic mapping of the mouse mdx locus

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1988 English Publisher:Elsevier BVJournal:Genomics, volume 3, pages 337-341 (issn: 0888-7543, Copyright policy )
Authors: Stephen D.M. Brown; Neil Brockdorff; J.E. Morgan; S.M. Forrest; G. R. Coulton; J. S. Cavanna; Kay E. Davies;

doi: 10.1016/0888-7543(88)90124-3

pmid: 3243547

Molecular and genetic mapping of the mouse mdx locus

Abstract

mdx is an X-linked muscular dystrophy mutant of the mouse and a putative homolog of the human X-linked muscular dystrophy locus--Duchenne muscular dystrophy (DMD). Utilizing a C57BL/10/Mus Spretus interspecific cross in which the mdx mutation was segregating, we have constructed a detailed genetic map around the mdx locus on the mouse X chromosome. We were unable to detect recombinants between mdx and exonic probes derived from the human DMD gene. These genetic data support the contention from biochemical studies (E.P. Hoffman, R. H. Brown, and L. M. Kunkel, 1987, Cell 51: 919-928) that DMD and mdx are homologous genes.

Related Organizations
Keywords

Genetic Markers, Male, X Chromosome, Chromosome Mapping, Muscular Dystrophy, Animal, Muscular Dystrophies, Mice, Inbred C57BL, Blotting, Southern, Mice, Genes, Haplotypes, Animals, Humans, Female

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
36
Average
Top 10%
Top 10%
gold