descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1988 English Publisher:Elsevier BVJournal:Biochemical Medicine and Metabolic Biology, volume 39, pages 5-10 (issn: 0885-4505,

Authors: T. N. Pattabiraman; Anuradha Kumar; K.Beena Rai;

doi: 10.1016/0885-4505(88)90051-5

pmid: 3355715

Glycated albumin and glycated hemoglobin levels in normal pregnancy

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Abstract

Glycated albumin levels showed a progressive increase during normal pregnancy. The mean values (mole hexose/mole protein) were 1.68 +/- 0.27 (n = 15) in nonpregnant women, 1.83 +/- 0.21 (n = 11) in first trimester, 2.00 +/- 0.41 (n = 13) in second trimester, and 2.42 +/- 0.49 (n = 15) in third trimester. Glycated hemoglobin levels indicated a biphase pattern with low values at midpregnancy (controls 0.29 +/- 0.05, first trimester 0.30 +/- 0.04, second trimester 0.27 +/- 0.05, and third trimester 0.33 +/- 0.04). The data suggest that glycated albumin reflects the decreased glucose tolerance in pregnancy better that glycated hemoglobin levels. The reasons for the differing pattern of the two glycated proteins are discussed.

Related Organizations

Kasturba Medical College
India

Keywords

Adult, Glycated Hemoglobin, Glycation End Products, Advanced, Pregnancy Trimester, Third, Pregnancy Trimester, First, Pregnancy, Reference Values, Pregnancy Trimester, Second, Humans, Female, Glycated Serum Albumin, Serum Albumin

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