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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Neuroscience Lettersarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Neuroscience Letters
Article . 1986 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Two types of electrocortical paroxysms in an inbred strain of rats

Authors: E.L.J.M. van Luijtelaar; Anton M.L. Coenen;

Two types of electrocortical paroxysms in an inbred strain of rats

Abstract

In 10 subjects of a particular inbred strain of rats (WAG/Rij), two types of spike-wave complexes were detected in the cortical electroencephalogram (EEG) during the two recording hours. The first type, already well-known, occurred in 8 of the 10 rats. This type was seen both during sleep and wakefulness and was accompanied by behavioural concomitants, reminiscent of human petit-mal epilepsy. A mean of 18 discharges/h was found. The second type, a novel one with a differential shape, occurred in 7 rats with a mean number of 14 discharges/h. In contrast to the first one, this spike-wave complex was not accompanied by behavioural correlates and was almost exclusively present during wakefulness. Four reasons make this strain of rats attractive as an additional animal model for epileptogenic activity: the occurrence of two types of spike-wave complexes, the high percentage of animals showing these phenomena, the genetic constitution of these rats and the fact that they are commercially available.

Related Organizations
Keywords

Cerebral Cortex, Male, Disease Models, Animal, Behavior, Animal, Epilepsy, Absence, Animals, Electroencephalography, Rats, Inbred Strains, Sleep, Rats

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    356
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
356
Top 1%
Top 1%
Top 10%
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