Lupus erythematosus (LE) includes a broadly defined group of related clinical illnesses that can affect the orofacial region. Discoid lupus erythematosus (DLE) is a generally benign mucocutaneous disease, whereas systemic lupus erythematosus (SLE) includes multisystem and organ involvement with significant mortality. Of intermediate severity, subacute LE (SCLE) often may share features found in both DLE and SLE.rm3 Although several different types of LE have been described, they all may have similar skin lesions. Ap proximately 20% to 30% of SLE patients and 15% to 20% of SCLE patients have discoid lesions sometime during their disease, most commonly involving the skin of the face and scalp. The discoid lesions appear as erythematous patches with scaling, telangiectasia, follicular plugging, atrophy, and scarring.4 Discoid lupus erythematosus also may include oral mucosal lesions in 3% to 20% of cases.’ Patients with DLE have minimal or absent systemic or serologic abnormalities, although it has been reported that 5% to 10% of patients eventually develop systemic manifestations.5 The following case report describes a patient with lip and facial lesions of DLE.