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Ring chromosomes and hematologic disorders

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1986 English Publisher:Elsevier BVJournal:Cancer Genetics and Cytogenetics, volume 23, pages 265-267 (issn: 0165-4608,

Authors: Photis Beris; Christiane Werner-Favre; Dominique Piguet; E. Engel;

doi: 10.1016/0165-4608(86)90188-3

pmid: 3464347

Ring chromosomes and hematologic disorders

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Abstract

Based on 5 years of cytogenetic evaluation in hematology, we report our observations on various hematologic proliferative disorders with ring chromosomes. Comparing our data to those previously published in the literature we analyzed the occurrence of the ring in relation to the age of onset, previous history of therapeutic or professional exposure to mutagenic agents, and mean survival. It is concluded that the presence of ring chromosomes may be linked to a poor prognosis.

Related Organizations

Geneva College
United States

Keywords

Adult, Aged, 80 and over, Chromosome Aberrations, Genetic Markers, Male, Middle Aged, Prognosis, Hematologic Diseases, Child, Preschool, Humans, Female, Ring Chromosomes, Aged

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