Anaphylactoid reactions to iodinated contrast material
Copyright policy )Anaphylactoid reactions to iodinated contrast material
A review of the literature involving anaphylactoid reactions to iodinated contrast material (ICM) suggests that the reactions are nonantibody-mediated but that a complex activation of inflammatory mediators occurs. Histamine release and/or complement activation has been demonstrated in both in vitro and in vivo experimental systems. It appears that pretreatment of selected cases (those patients previously exhibiting an anaphylactoid reaction) is effective in reducing the frequency and severity of subsequent reactions when readministration is necessary.
- University of Tennessee at Knoxville United States
- University of Tennessee System United States
- University of Tennessee Health Science Center United States
Time Factors, Contrast Media, Complement System Proteins, Middle Aged, Histamine Release, Antigen-Antibody Reactions, Adrenal Cortex Hormones, Histamine H1 Antagonists, Humans, Female, Child, Anaphylaxis, Iodine
Time Factors, Contrast Media, Complement System Proteins, Middle Aged, Histamine Release, Antigen-Antibody Reactions, Adrenal Cortex Hormones, Histamine H1 Antagonists, Humans, Female, Child, Anaphylaxis, Iodine
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