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Stimulation of dieldrin metabolism by DDT

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1967Publisher:Elsevier BVJournal:Toxicology and Applied Pharmacology, volume 11, pages 68-71 (issn: 0041-008X,

Authors: Joseph C. Street; R.W. Chadwick;

doi: 10.1016/0041-008x(67)90027-0

pmid: 6056156

Stimulation of dieldrin metabolism by DDT

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Abstract

Abstract The excretion of polar metabolites of dieldrin by DDT-treated female rats greatly exceeded that by rats given only dieldrin- 14 C. Increased metabolite excretion was observed in both feces and urine, the relative increase being greater in the urinary products. The chromatographic properties of the major urinary dieldrin metabolite in DDT-stimulated rats did not match those of trans -dihydroxydihydroaldrin, the principal urinary metabolite in the rabbit.

Related Organizations

Utah State University
United States
Dixie State University
United States

Keywords

Carbon Isotopes, Chromatography, Dieldrin, Feces, Animals, Female, DDT, Rats

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