Abstract Maxillofacial prosthodontics is an essential adjunct to reconstructive surgery in many types of deformations and malformations of the jaws. Among the indications for prosthetic appliances are: (1) severe facial injuries with loss of bony framework, (2) defects of the mandible requiring bone grafting, (3) micrognathia, and (4) nasomaxillary atresia. The epithelial inlay technique for skin grafting in the oral or nasal cavities has been described, and a number of applications of the epithelial inlay technique have been illustrated. Close collaboration of the plastic surgeon and the prosthodontist is essential in the treatment of many types of orofacial defects.