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Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1985Publisher:Elsevier BVJournal:International Journal of Biochemistry, volume 17, pages 187-193 (issn: 0020-711X,

Authors: Leigh C. Ward; Lyle E. Carrington; Ross Daly;

doi: 10.1016/0020-711x(85)90113-2

pmid: 3924678

Ethanol and leucine oxidation—I. Leucine oxidation by the rat in vivo

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Abstract

The effect of ethanol upon the oxidation of leucine by the rat in vivo was determined. The rate of leucine oxidation was not significantly altered by chronic administration of ethanol (20% v/v solution as drinking water for 28 days). Ethanol administered acutely (8 g kg 0.73) significantly decreased leucine oxidation by the rat in vivo. This decrease appeared to be independent of a more general depression of oxidation metabolism. Decrease in leucine oxidation by ethanol is discussed in relation to the regulation of tissue leucine pool sizes in vivo.

Related Organizations

University of Queensland
Australia
University of Queensland
Australia

Keywords

Male, Aminoisobutyric Acids, Ethanol, Rats, Inbred Strains, Carbon Dioxide, Rats, Kinetics, Leucine, Animals, Carbon Radioisotopes, Oxidation-Reduction

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	20
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%